RE-USE OF ESTABLISHED DRUGS FOR ANTI-METASTATIC INDICATIONS

Re-Use of Established Drugs for Anti-Metastatic Indications

Most patients that die from cancer do not die due to the primary tumor but due to the development of metastases.However, there is currently still no drug on the market that specifically Bags addresses and inhibits metastasis formation.This lack was, in the past, largely due to the lack of appropriate screening models, but recent developments have e

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Browning Epicardial Adipose Tissue: Friend or Foe?

The epicardial adipose tissue (EAT) is the visceral fat depot of the heart which is highly plastic and in direct contact with myocardium and coronary arteries.Because of its singular proximity with the myocardium, the adipokines and pro-inflammatory molecules secreted by this tissue may directly affect the metabolism of the heart and coronary arter

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